BioVascular Overview
BioVascular Inc. is a privately held biotechnology company that develops drugs and devices for the control of intimal hyperplasia associated with vascular procedures and control of risk factors associated with cardiovascular morbidity and mortality.
BioVascular's lead product, saratin, is a polypeptide produced by recombinant means in yeast. This product was licensed from Merck, KGaA in...More»
BioVascular Inc. is a privately held biotechnology company that develops drugs and devices for the control of intimal hyperplasia associated with vascular procedures and control of risk factors associated with cardiovascular morbidity and mortality.
BioVascular's lead product, saratin, is a polypeptide produced by recombinant means in yeast. This product was licensed from Merck, KGaA in 2005. BioVascular began human clinical trials of saratin for hemodialysis graft access in late 2006 and will begin human trials in the treatment of peripheral artery grafts in early 2007.
BioVascular’s second product utilizes a novel mechanism for reduction of a recently defined cardiovascular risk factor. This product will enter human studies in mid 2007.«Less
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Funding
| Date | Type | Capital Amount | Post-Money Valuation | Investors |
|---|---|---|---|---|
| 02/2008 | Series C | 11M | Unknown |
Products
| Name: | Saratin |
| Product URL: | http://www.biovascularinc.com/saratin.html |
| Description: | Saratin is a 12 kDa polypeptide originally identified as a component of leech saliva (Hirudo medicinalis) and currently produced as a recombinant protein in yeast (Hansenula polymorpha). Saratin is designed to be applied during surgery to the endovascular surface where it coats the exposed collagen and inhibits vWF-dependent binding of platelets to arterial wall collagens. In preventing the vWF-mediated platelet adhesion to damaged vessels, saratin blocks the first step in a sequence of events involving platelet aggregation and activation and may thereby prevent the subsequent thrombus formation and intimal hyperplasia that occurs in a range of vascular surgical and endovascular procedures. |
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